Severe Pulmonary Disease Associated with Electronic CigaretteProduct Use Interim Guidance MMWR E cigarette, or Vaping Product, Use Associated Lung Injury (EVALI) Fact Sheets Yale Medicine A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, COPD: Causes, Symptoms & Treatment Options Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disorder characterized by persistent airflow limitation that is not fully reversible. It develops gradually, most often due to long term exposure to harmful E cigarette use increases risk for developing major respiratory diseases