Frontiers Research progress of glutathione peroxidase family (GPX) in redoxidation The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities TJ. Glutathione peroxidase is an important enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. As a component of the glutathione cycle, it protects the liver from reactive oxygen metabolites. Selenocysteine Glutathione peroxidase 4: a new player in neurodegeneration? Molecular Psychiatry Figure 3 from Glutathione Peroxidase 1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities Semantic Scholar Full article: Antioxidant Role in Critically Ill Patients with Vasodilatory Shock: Does Glutathione Peroxidase Correlate to Severity of Tissue Hypoxia and Organ Failure