Therapeutic Potential of Targeting the Ghrelin Pathway Figure 3 from Ipamorelin, the first selective growth hormone secretagogue. Semantic Scholar Ipamorelin and CJC 1295 are almost always discussed together in research circles, and the reason comes down to receptor pharmacology. The two peptides work through entirely different but complementary mechanisms that produce a Table 3 from Ipamorelin, the first selective growth hormone secretagogue. Semantic Scholar Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren Nature Communications Growth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target eNeuro