The distance between a compound demonstrating efficacy in preclinical research and that compound appearing in a physician's standard toolkit can span a generation. The mechanisms by which NAC addresses oxidative stress, glutamate Your Glutathione Index Defines How Your Cells Are Ageing Pathophysiological Links Between Myocardial Infarction and Anxiety Disorder, Major Depressive Disorder, Bipolar Disorder and Schizophrenia Glutamine vs. Glutathione: Their Relationship and Glutamate's Role Troscriptions Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry Translational Psychiatry Counteracting Effects of Glutathione on the Glutamate Driven Excitation Inhibition Imbalance in First Episode Schizophrenia: A 7T MRS and Dynamic Causal Modeling Study