Clinical Challenge: Dark Lesion on Lower Lip MPR Labial melanotic macule 3 sessions of Q switched Nd:YAG and the pigment has cleared beautifully. Precise targeting. Minimal downtime. Predictable results. #lippigmentation #lasertreatmentclinic Dark Spot on Lip: Harmless or Serious? What to Check First La Bouche Parfaite Mucosal melanocytic macules Oral melanoma and other pigmentations: when to biopsy? Lambertini 2018 Journal of the European Academy of Dermatology and Venereology Wiley Online Library Mara Ever wondered what those little brown spots are that are often found on the lip? Many refer to them as a freckle but the medical term is melanotic macules.