Mycotoxin induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549 ScienceDirect Mycotoxins are toxic. But they are only one of many stressors affecting the extracellular matrix. Ochratoxin, aflatoxins, and trichothecenes increase oxidative stress, deplete glutathione, disrupt mitochondria, and activate inflammatory signaling. That Mold mycotoxins deplete the body of its master antioxidant glutathione. In true Tolkien homage, I refer to glutathione as 'the one antioxidant to rule them all. It's a critical detoxifier of How Mycotoxins Trigger Mast Cell Activation and Brain Inflammation Identification of cytotoxic, glutathione reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion ScienceDirect Unveiling the Hidden Threat: Exploring the Impact of Mold and Mycotoxins Austin MD Aesthetics & Wellness