Full article: Trimethylamine N oxide formation, the bacterial taxa involved and intervention strategies to reduce its concentration in the human body Can diet modulate trimethylamine N oxide (TMAO) production? What do we know so far? European Journal of Nutrition Springer Nature Link Nutrition Dark Matter and Impact on Health Dr. Leonardo Riella The anti atherogenic bioactive metabolites of natural medicine generated by host microbe co metabolism system. The terminal metabolites of low bioavailable polysaccharides are SCFAs, among which propionate and butyrate can effectively attenuate TMAO metaorganismal pathway and chronic inflammatory diseases Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine (