Glucose 6 Phosphate Dehydrogenase Deficiency Hematology & Oncology UWorld Medical Library Glucose 6 phosphate dehydrogenase deficiency Knowledge @ AMBOSS In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione Blister Cell in G6PD Deficiency , Red Blood Cell with a clear vacuole like area on its membrane, resembling a blister., It usually results when splenic macrophages remove precipitated Heinz Anemia: Part 10 Glucose 6 Phosphate Dehydrogenase Deficiency (G6PD Deficiency) Labpedia.net High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level